Long-term culture based on dendritic cell activity/inactivity control technology
Development of regulatory techniques that exist in a functionally inactive state while maintaining the survival of primary dendritic cells separated from immune tissue to devour antigens and turn into active forms if immune or inflammatory stimulation is received
Development of a culture method that can be cultured without activation by a combination of fibronectin-derived peptides (PHSRN, RGD, and LDV peptides) and induce activity of dendritic cells by adding stimulants
T cell activation technology by primary dendritic cells
Primary dendritic cells vs Differentiated dendritic cells
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Differences in subtypes between primary dendritic cells and inflammatory differentiated dendritic cells → Differences in T cell activity → Differences in anti-tumor efficacy
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Separated super dendritic cells → Presence of the same subtype in the body
Development of the primary dendritic cell as a powerful anti-cancer immune cell therapy
Identification of Dendritic Cell Self-Activation Regulatory Substances
Discovery of Self-Activating Target-Based Inhibitors for Dendritic Cells
Using the developed system, various kinds of regulatory factors that can secure the defense of patent rights and the rights of family patents are identified, and patent rights are secured
