To determine the best iron supplements available, the Forbes Health editorial team consulted a panel of four accredited experts who provided their top picks and why they recommend them. The editorial team solely determined star ratings, based on average user rating and cost. Note: This ranking features iron supplements for adults that (unless stated or instructed by a doctor) should not be given to or consumed by children, as consuming too much iron can lead to toxicity.
This supplement is not only gluten-free and GMO-free, but also does not contain wheat, eggs, tree nuts, peanuts, artificial colors and sweeteners, coatings and shellacs and unnecessary binders, fillers and preservatives. The iron in this supplement is iron glycinate and 50% iron aspartate.
In addition to being GMO-free and gluten-free, this supplement from Solgar is free from wheat, dairy, soy, yeast, sugar, sodium and artificial colors, sweeteners and flavors. It features iron bisglycinate chelate.
For the Best Iron Supplements Of 2023, the Forbes Health editorial team consulted a panel of four accredited experts on their top picks for iron supplements and why they recommend them. Star ratings were assigned solely by the editorial team, based on factors including cost and user rating.
Talk to your doctor before incorporating an iron supplement into your wellness routine, as they can interfere with certain medications and are not recommended for people with certain conditions. Iron, Vitamin C, and Superfoods...All in One Capsule
Iron supplements are best taken on an empty stomach, but some people may need to take them with a small amount of food to avoid side effects. You should not take iron supplements at the same time as milk, calcium or antacids (take them at least two hours after), as well as high-fiber foods or caffeine. Taking an iron supplement with vitamin C may help your body absorb it more effectively.
Although many people in the U.S. get enough iron from their diet, some must take additional amounts to meet their needs. For example, iron is sometimes lost with slow or small amounts of bleeding in the body that you would not be aware of and which can only be detected by your doctor. Your doctor can determine if you have an iron deficiency, what is causing the deficiency, and if an iron supplement is necessary.
Problems in children have not been reported with intake of normal daily recommended amounts. Iron supplements, when prescribed by your health care professional, are not expected to cause different side effects in children than they do in adults. However, it is important to follow the directions carefully, since iron overdose in children is especially dangerous.
Problems in older adults have not been reported with intake of normal daily recommended amounts. Elderly people sometimes do not absorb iron as easily as younger adults and may need a larger dose. If you think you need to take an iron supplement, check with your health care professional first. Only your health care professional can decide if you need an iron supplement and how much you should take.
It is especially important that you are receiving enough vitamins and minerals when you become pregnant and that you continue to receive the right amount of vitamins and minerals throughout your pregnancy. Healthy fetal growth and development depend on a steady supply of nutrients from mother to fetus. During the first 3 months of pregnancy, a proper diet usually provides enough iron. However, during the last 6 months, in order to meet the increased needs of the developing baby, an iron supplement may be recommended by your health care professional.
It is especially important that you receive the right amounts of vitamins and minerals so that your baby will also get the vitamins and minerals needed to grow properly. Iron normally is present in breast milk in small amounts. When prescribed by a health care professional, iron preparations are not known to cause problems during breast-feeding. However, nursing mothers are advised to check with their health care professional before taking iron supplements or any other medication. Taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or infant and should be avoided.
Do not take iron supplements and antacids or calcium supplements at the same time. It is best to space doses of these 2 products 1 to 2 hours apart, to get the full benefit from each medicine or dietary supplement.
The preparation of the isotope labelled ferrous sulphate (FeSO4) tablets was similar to the method used in the commercial preparation of the supplementation programme tablets6. The elemental 57Fe and 58Fe isotopes (Chemgas, France) were dissolved separately in 0.01 M H2 SO4 (Merck, Ultrapure grade) solution to get a final concentration of 3 mg 57Fe or 58Fe/ml of iron sulphate solution5. All the procedures were carried out in a clean room under the fume hood. The tablets contained FeSO4 equivalent to 100 mg elemental Fe and 0.5 mg folic acid. The elemental iron contained 97 mg of 56Fe and 3 mg of stable isotope of 57Fe as the sulphate salt in the ECFS tablet, and 58Fe in the UCFS tablet. All chemicals were pharma grade (Yarrow Chemical, Mumbai); the 57FeSO4 or 58FeSO4 was slowly added as a 3 mg 57FeSO4 or 58FeSO4/ml solution to the natural FeSO4 granules and dried. These were blended with excipients, loaded into a tablet press and punched as tablets in a twelve station-punching machine (CIP Machinery Pvt. Ltd., Ahmedabad). Tablets incorporated with 57FeSO4 were then film coated with enteric coating (methahexa copolymer, 6% w/w). Similarly, the tablets incorporated with 58FeSO4 were film coated with titanium oxide as a colourant and opacifier. These procedures were carried out at a registered pharmaceutical research facility (Karnataka College of Pharmacy, Bengaluru, registered under the Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka, India).
Each woman received the isotope labelled ECFS or UCFS in a randomized manner on two consecutive days. On day one, women were asked to report to the metabolic ward in a fasted state, where their anthropometry was measured and a medical history was taken, following which, a rice-based breakfast (Two Idlies with chutney) was served. Sixty minutes after breakfast, the participant consumed either ECFS or UCFS with 100 ml of water, and no food or drink was allowed for 3 h thereafter. The next day, the second isotope labelled tablet was administered with the same process. A blood sample (6 ml) was drawn 15 days after the first day of dosing. Each isotopically enriched blood sample was analyzed in triplicate to measure the shift in isotopic composition of iron in Hb, using a Thermal Ionization Mass Spectrometer (Triton, Thermo Scientific, Germany). The erythrocyte incorporation technique was used to measure fractional iron absorption; the methodology has been described earlier5.
Iron combination supplements are used to treat anemia and iron deficiencies by increasing the red blood cell levels in the body and providing more iron. Iron combination supplements also contain another nutrient other than iron, for example, vitamin C or other dietary supplements. A commonly used iron combination supplement is Iron 100-vitamin C Fe C.
Background: There is limited information on zinc deficiency in pregnant women. The present study aimed to assess the serum zinc (S. zinc) levels and its relation to iron deficiency anemia (IDA) in pregnant women. Patients and Methods: In this case-control study, S. zinc concentrations of 34 individuals diagnosed with IDA, 20 non-iron deficiency anemic pregnant women, and 32 non-anemic apparently healthy individuals were measured. Results: S. zinc was significantly lower in the IDA group (49.59 ng/dL) compared to the healthy controls (55.78; P = 0.018). The individuals in three groups were comparable in the number of persons with zinc deficiency. The study showed that S. zinc has a positive correlation with Hb (r = 0.281, P = 0.011). In addition, S. zinc had a positive correlation with hematocrit (HCT, r = 0.305, P = 0.005) and a negative correlation with serum iron (S. iron, r = 0.242, P = 0.029). Conclusions: This investigation showed that the patients with IDA have a significantly lower concentration of S. zinc and it was substantially positively correlated with Hb, red blood cell, and HCT and negatively with S. iron. Further studies are still needed to evaluate the benefits of zinc and iron supplementation in IDA patients.
Scientific attention to the role of specific nutrients, especially micronutrients, in healthy pregnancy has grown steadily in recent years, beginning with numerous fields of studies of pregnancy in developing countries. Zinc and iron are micronutrients whose requirements increase with pregnancy. Pregnant women worldwide are frequently iron and zinc deficient. Low birth weight is associated with maternal anemia and, in some circumstances, with low iron and zinc status. Therefore, cosupplementation of iron and zinc during pregnancy is common. Although iron supplementation programs are successful, studies suggest that zinc supplementation negatively affects maternal iron metabolism.
Competing interests: D.I.A.P. is one of the inventors of the IHAT iron supplementation technology, for which she could receive future awards to inventors through the MRC Awards to Inventor scheme. Notwithstanding, the authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Background: Iron deficiency and its associated anaemia (IDA) are the leading forms of micronutrient malnutrition worldwide. Here we describe the rationale and design of the first clinical trial evaluating the efficacy and safety of an innovative nano iron supplement, iron hydroxide adipate tartrate (IHAT), for the treatment of IDA in young children (IHAT-GUT trial). Oral iron is often ineffe